Chronic Bystander Infections and Immunity to Unrelated Antigens
نویسندگان
چکیده
منابع مشابه
HLA-KIR Interactions and Immunity to Viral Infections
Host genetic factors play a central role in determining the clinical phenotype of human diseases. Association between two polymorphic loci in human genome, human leukocyte antigen (HLA) and killer cell immunoglobulin-like receptors (KIRs), and genetically complex infectious disease, particularly those of viral etiology, have been historically elusive. Hence, defining the influence of genetic di...
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host genetic factors play a central role in determining the clinical phenotype of human diseases. association between two polymorphic loci in human genome, human leukocyte antigen (hla) and killer cell immunoglobulin-like receptors (kirs), and genetically complex infectious disease, particularly those of viral etiology, have been historically elusive. hence, defining the influence of genetic di...
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It has been proposed that long-lived memory T cells generated by vaccination or infection reside within a memory compartment that has a finite size. Consequently, in a variety of acute infection models interclonal competition has been shown to lead to attrition of preexisting memory CD8+ T cells. Contrary to expectations, therefore, we found that chronic Leishmania donovani infection of Listeri...
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ژورنال
عنوان ژورنال: Cell Host & Microbe
سال: 2012
ISSN: 1931-3128
DOI: 10.1016/j.chom.2012.10.001